| Professor Andrew Scholey Director, Centre for Human Psychopharmacology Swinburne University, Melbourne, VIC 3122 Australia Email: andrew@scholeylab.com (or click icon top right) |
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My research...I
am interested in the way in which substances (food, nutrition,
nutrients, drugs and alcohol etc.) change the human brain, physiology and behaviour. I
have led over 100 studies of into the human biobehavioural
effects of natural products, and their neurocognition-enhancing and
anti-stress/anxiolytic properties including numerous first-into-human
neurocognitive clinical trials. I work closely with industry to
translate research into evidence-based interventions for optimum brain
health.
Broadly my research can be divided into the following themes:
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Nutritional interventions for brain health |
Alcohol and drugs |
Alcohol Hangover |
Physiological response to mental effort |
Glucose and oxygen effects on cognitive performance |
| This
research examines the potential for nutritional interventions,
including diet, isolated nutrients and botanical extracts to
improve mood and cognitive function. Certain
classes of bioactive nutrients appear to improve mood and
cognition acutely. Others may protect against age-associated cognitive
decline. |
This stream of research examines the acute and chronic effects of recreatrional drugs (including MDMA/Ecstasy and alcohol). Alcohol intoxication "uncalibrates" people so error monitoring and feedback is impaired. Other recreational drugs have long-term negative behavioural effects. | This research examines the cognitive, mood and physiological effects of alcohol hangover - an area which is surprisingly under-researched. Hangover is associated with negative mood and cognitive deficits whoich suggest reduced cognitive resources. These have profound effects for day-to-day performance. | There
is a correspondence between the subjective experience of
cognitive strain and the utilisation of central resources. At
the same time, during mental effort a number of physiological responses
serve to facilitate provision of energetic respources. Some cognition
enhancing interventions have similar effects. |
The
brain is highyly metabolically active, utilising a large percentage of
the body's glucose and oxygen. This research examined the cognition
-enhancing effects of administration of glucose and oxygen on cognitive
function. These effects seem to be most evident under conditions of
high mental effort. |
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